KRT13 Guinea Pig Polyclonal Antibody

CAT#: BP5076

KRT13 guinea pig polyclonal antibody, Serum


USD 405.00

2 Weeks*

Size
    • 100 ul

Product Images

Specifications

Product Data
Applications IF, IHC, WB
Recommended Dilution Immunoblotting: 1/3000 (ECL method).
Immunohistochemistry on Frozen Sections:
1/200.
Immunohistochemistry on Paraffin Sections:
1/100 (after microwave treatment).
Immunohistochemistry on Cytological Material.
Positive Control:
Squamous epithelium of esophagus, gingival, palate, vagina (staining all of the suprabasal layers).
Incubation Time:
1h at RT, extended with Paraffin Sections.
Reactivities Human, Mouse
Host Guinea Pig
Clonality Polyclonal
Immunogen Synthetic peptide (TTTSSASVTTTSNA-C) of Human keratin K13 (formerly also designated cytokeratin 13), coupled to KLH.
Specificity This antibody recognizes Acidic Human keratin K13 (Mr 55 000).
Excellent marker to discriminate non-cornified squamous epithelia (esophagus, vagina, gingival) from those of different origin. Negative on foot sole, scalp.
Tumors Specifically Detected: Several squamous cell carcinomas, e.g. cervix carcinoma; transitional cell carcinoma of the bladder; craniopharyngioma.
Formulation State: Serum
State: Stabilized Liquid antiserum
Stabilizer: 0.5% BSA
Preservative: 0.09% Sodium Azide
Storage Store the antibody undiluted at 2-8°C.
Stability Shelf life: one year from despatch.
Gene Name keratin 13
Background Cytokeratin 13 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus.
Synonyms CK-13, CK13, Keratin-13, KRT13, K13, KRT-13
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.