LOC100653049 Guinea Pig Polyclonal Antibody
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Product Data | |
Applications | IHC, WB |
Recommended Dilution | Immunoblotting: 1 : 2,000, ECL method. Immunohistochemistry on frozen sections: 1/200; 1h at RT. NOTE: For enhancement of cortex staining preincubate fixed sections with 0.1 Triton X-100 (in PBS) for 1 - 5 min prior to first antibody incubation step. |
Reactivities | Human, Mouse |
Host | Guinea Pig |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human acidic hair (trichocytic) keratin K34 (formerly also designated keratin hHa4; GPC GTS QKG CCN), coupled to KLH. |
Specificity | The antiserum stains specifically human hair keratin K34 expressed in the upper hair cortex cells. Reacts with human and mouse. |
Formulation | State: Serum State: Liquid serum contains 0.09% sodium azide |
Database Link | |
Background | KRT34 is a type I hair keratin. Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins are acidic proteins and are usually found as a heterotetramer with two molecules of a type II keratin. |
Synonyms | KRT-34, Keratin, type I cuticular Ha4, HHA4, HKA4, KRTHA4, Hair keratin, type I Ha4, Keratin34 |
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