Neurotrophin 4 (NTF4) Mouse Monoclonal Antibody [Clone ID: OTI2E8]
CAT#: CF500034
Carrier-free (BSA/glycerol-free) NT4 mouse monoclonal antibody, clone OTI2E8 (formerly 2E8)
Formulation: Standard
Other products for "NTF4"
Specifications
Product Data | |
Clone Name | OTI2E8 |
Applications | IF, IHC, WB |
Recommended Dilution | WB 1:5000, IHC 1:50, IF 1:50 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 81-210 human NT4 (NP_006170) produced in E.coli. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 22.2 kDa |
Gene Name | Homo sapiens neurotrophin 4 (NTF4), mRNA. |
Database Link | |
Background | NT4 is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of NT4 is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NT4-deficient mice only show minor cellular deficits and develop normally to adulthood. |
Synonyms | 5; GLC1O; GLC10; NT-4; NT-5; NT4; NT5; NTF5 |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | MAPK signaling pathway, Neurotrophin signaling pathway |
Documents
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