Adenylate Kinase 1 (AK1) Mouse Monoclonal Antibody [Clone ID: OTI8A1]

CAT#: CF500322

Carrier-free (BSA/glycerol-free) AK1 mouse monoclonal antibody, clone OTI8A1 (formerly 8A1)

Formulation: Standard Carrier Free


  View other "OTI8A1" antibodies (2)

USD 465.00

4 Weeks*

Size
    • 100 ug

Specifications

Product Data
Clone Name OTI8A1
Applications FC, IF, WB
Recommended Dilution WB 1:2500~5000, IF 1:100, FLOW 1:100
Reactivities Human, Monkey, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human AK1 (NP_000467) produced in HEK293T cell.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 21.6 kDa
Gene Name Homo sapiens adenylate kinase 1 (AK1), transcript variant 1, mRNA.
Background Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.
Synonyms HTL-S-58j
Reference Data
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Purine metabolism

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.