QPRT Mouse Monoclonal Antibody [Clone ID: OTI4B4]

CAT#: CF501523

Carrier-free (BSA/glycerol-free) QPRT mouse monoclonal antibody, clone OTI4B4 (formerly 4B4)

Formulation: Standard Carrier Free


  View other "OTI4B4" antibodies (2)

USD 465.00

4 Weeks*

Size
    • 100 ug

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Specifications

Product Data
Clone Name OTI4B4
Applications FC, WB
Recommended Dilution WB 1:500~2000, FLOW 1:100
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human QPRT (NP_055113) produced in HEK293T cell.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 30.6 kDa
Gene Name Homo sapiens quinolinate phosphoribosyltransferase (QPRT), transcript variant 1, mRNA.
Background This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.
Synonyms HEL-S-90n; QPRTase
Reference Data
Protein Pathways Metabolic pathways, Nicotinate and nicotinamide metabolism

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.