HDAC1 Mouse Monoclonal Antibody [Clone ID: OTI5C3]

CAT#: CF502142

Carrier-free (BSA/glycerol-free) HDAC1 mouse monoclonal antibody, clone OTI5C3 (formerly 5C3)

Formulation: Standard Carrier Free


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USD 465.00

4 Weeks*

Size
    • 100 ug

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Specifications

Product Data
Clone Name OTI5C3
Applications FC, IF, WB
Recommended Dilution WB 1:200~500, IF 1:100, FLOW 1:100
Reactivities Human, Monkey, Mouse, Rat
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Full length human recombinant protein of human HDAC1 (NP_004955) produced in HEK293T cell.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 54.9 kDa
Gene Name Homo sapiens histone deacetylase 1 (HDAC1), mRNA.
Background Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq]
Synonyms GON-10; HD1; RPD3; RPD3L1
Reference Data
Protein Families Adult stem cells, Druggable Genome, Stem cell - Pluripotency, Stem cell relevant signaling - DSL/Notch pathway, Transcription Factors
Protein Pathways Cell cycle, Chronic myeloid leukemia, Huntington's disease, Notch signaling pathway, Pathways in cancer

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.