PDE1B Mouse Monoclonal Antibody [Clone ID: OTI6E4]
CAT#: CF503319
Carrier-free (BSA/glycerol-free) PDE1B mouse monoclonal antibody, clone OTI6E4 (formerly 6E4)
Formulation: Standard
Other products for "PDE1B"
Specifications
Product Data | |
Clone Name | OTI6E4 |
Applications | FC, IF, IHC, WB |
Recommended Dilution | WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human PDE1B(NP_000915) produced in HEK293T cell. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 61.2 kDa |
Gene Name | Homo sapiens phosphodiesterase 1B (PDE1B), transcript variant 1, mRNA. |
Database Link | |
Background | Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1B, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]). [supplied by OMIM] |
Synonyms | PDE1B1; PDES1B |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Calcium signaling pathway, Progesterone-mediated oocyte maturation, Purine metabolism |
Documents
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Resources
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