SLUG (SNAI2) Mouse Monoclonal Antibody [Clone ID: OTI2B12]

CAT#: CF504907

Carrier-free (BSA/glycerol-free) SNAI2 mouse monoclonal antibody, clone OTI2B12 (formerly 2B12)

Formulation: Standard Carrier Free


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USD 465.00

In Stock*

Size
    • 100 ug

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Specifications

Product Data
Clone Name OTI2B12
Applications IF, WB
Recommended Dilution WB 1:1000, IF 1:100
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen negative.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 29.8 kDa
Gene Name Homo sapiens snail family transcriptional repressor 2 (SNAI2), mRNA.
Background This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq]
Synonyms SLUG; SLUGH1; SNAIL2; WS2D
Reference Data
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Adherens junction

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