P cadherin (CDH3) Mouse Monoclonal Antibody [Clone ID: OTI2D5]

CAT#: CF506403

Carrier-free (BSA/glycerol-free) CDH3 mouse monoclonal antibody, clone OTI2D5 (formerly 2D5)

Formulation: Standard Carrier Free


  View other "OTI2D5" antibodies (2)

USD 465.00

In Stock*

Size
    • 100 ug

Other products for "CDH3"

Specifications

Product Data
Clone Name OTI2D5
Applications IF, IHC, WB
Recommended Dilution WB 1:4000, IHC 1:150, IF 1:100
Reactivities Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Full length human recombinant protein of human CDH3(NP_001784) produced in HEK293T cell.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 88.8 kDa
Gene Name Homo sapiens cadherin 3 (CDH3), transcript variant 1, mRNA.
Background This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy. [provided by RefSeq, Jul 2008]
Synonyms CDHP; HJMD; PCAD
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs)

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