Fibrinogen gamma chain (FGG) Mouse Monoclonal Antibody [Clone ID: OTI2D2]

CAT#: CF507132

Carrier-free (glycerol/BSA-free) FGG mouse monoclonal antibody, clone OTI2D2 (formerly 2D2)

Formulation: Standard Carrier Free


  View other "OTI2D2" antibodies (2)

USD 465.00

In Stock*

Size
    • 100 ug

Specifications

Product Data
Clone Name OTI2D2
Applications IHC, WB
Recommended Dilution WB 1:400~4000, IHC 1:150
Reactivities Human, Monkey, Mouse
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human FGG(NP_000500) produced in HEK293T cell.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 46.4 kDa
Gene Name Homo sapiens fibrinogen gamma chain (FGG), transcript variant gamma, mRNA.
Background The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul
Synonyms fibrinogen; fibrinogen gamma chain; gamma chain; gamma polypeptide
Reference Data
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Complement and coagulation cascades

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