HBS1L Mouse Monoclonal Antibody [Clone ID: OTI1F11]
CAT#: CF800566
Carrier-free (BSA/glycerol-free) HBS1L mouse monoclonal antibody, clone OTI1F11 (formerly 1F11)
Formulation: Standard
Other products for "HBS1L"
Specifications
Product Data | |
Clone Name | OTI1F11 |
Applications | WB |
Recommended Dilution | WB 1:2000 |
Reactivities | Human, Monkey, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 1-260 of human HBS1L (NP_006611) produced in E.coli. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 75.3 kDa |
Gene Name | Homo sapiens HBS1 like translational GTPase (HBS1L), transcript variant 1, mRNA. |
Database Link | |
Background | This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq] |
Synonyms | EF-1a; eRF3c; ERFS; HBS1; HSPC276 |
Reference Data |
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