TRIF (TICAM1) Mouse Monoclonal Antibody [Clone ID: OTI1G7]
CAT#: CF800679
Carrier-free (BSA/glycerol-free) TICAM1 mouse monoclonal antibody, clone OTI1G7 (formerly 1G7)
Formulation: Standard
Other products for "TICAM1"
Specifications
Product Data | |
Clone Name | OTI1G7 |
Applications | WB |
Recommended Dilution | WB 1:2000 |
Reactivities | Human, Monkey |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 120-420 of human TICAM1 (NP_891549) produced in E.coli. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 76.2 kDa |
Gene Name | Homo sapiens toll like receptor adaptor molecule 1 (TICAM1), mRNA. |
Database Link | |
Background | This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response. [provided by RefSeq, Jan 2012] |
Synonyms | IIAE6; MyD88-3; PRVTIRB; TICAM-1; TRIF |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Toll-like receptor signaling pathway |
Documents
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