DUSP10 Mouse Monoclonal Antibody [Clone ID: OTI2H1]

CAT#: CF806771

Carrier-free (BSA/glycerol-free) DUSP10 mouse monoclonal antibody, clone OTI2H1 (formerly 2H1)

Formulation: Standard Carrier Free


  View other "OTI2H1" antibodies (2)

USD 465.00

In Stock*

Size
    • 100 ug

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Specifications

Product Data
Clone Name OTI2H1
Applications IHC, WB
Recommended Dilution WB 1:2000
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 180-482 of human DUSP10(NP_009138) produced in E.coli.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name Homo sapiens dual specificity phosphatase 10 (DUSP10), transcript variant 1, mRNA.
Background Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Synonyms MKP-5; MKP5
Reference Data
Protein Families Druggable Genome, Phosphatase
Protein Pathways MAPK signaling pathway

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