Somatostatin Receptor 3 (SSTR3) Mouse Monoclonal Antibody [Clone ID: OTI9A7]

CAT#: CF808922

Carrier-free (BSA/glycerol-free) SSTR3 mouse monoclonal antibody,clone OTI9A7

Product Images

Equivalent amounts of lysates (5 ug per lane) of SSTR1, 2, 3, 4 and 5 peptide (from lane 1 to 5) were separated by SDS-PAGE and immunoblotted with anti-SSTR3 antibody (1:500).

Specifications

Product Data

• Clone Name: OTI9A7
• Applications: WB
• Recommended Dilution: WB 1:500
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human SSTR3:(NOVA)(NP_001042). The exact sequence is proprietary.
• Formulation: Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
• Reconstitution Method: For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 45.7 kDa
• Gene Name: Homo sapiens somatostatin receptor 3 (SSTR3), transcript variant 1, mRNA.
• Database Link:
  NP_001042
  Entrez Gene 20607 MouseEntrez Gene 171044 RatEntrez Gene 6753 Human
  UniProt ID P32745
• Background: This gene encodes a member of the somatostatin receptor protein family. Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This protein is functionally coupled to adenylyl cyclase. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
• Synonyms: SS-3-R; SS3-R; SS3R; SSR-28

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction