BNP (NPPB) Mouse Monoclonal Antibody [Clone ID: OTI3H2]

CAT#: CF809065

Carrier-free (BSA/glycerol-free) NPPB mouse monoclonal antibody, clone OTI3H2 (formerly 3H2)

Formulation: Standard Carrier Free


  View other "OTI3H2" antibodies (2)

USD 465.00

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Size
    • 100 ug

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Specifications

Product Data
Clone Name OTI3H2
Applications LMNX, WB
Recommended Dilution WB 1:2000
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 27-102 of human NPPB (NP_002512) produced in E.coli.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 11.9 kDa
Gene Name Homo sapiens natriuretic peptide B (NPPB), mRNA.
Background This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Jul 2008]
Synonyms BNP
Reference Data
Protein Families Druggable Genome, Secreted Protein, Stem cell - Pluripotency

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