GMPR1 (GMPR) Mouse Monoclonal Antibody [Clone ID: OTI1E8]

CAT#: CF811370

Carrier-free (BSA/glycerol-free) GMPR mouse monoclonal antibody,clone OTI1E8

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GMPR (RC202453, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GMPR (1:500). Positive lysates LY416357 (100ug) and LC416357 (20ug) can be purchased separately from OriGene.

Specifications

Product Data

• Clone Name: OTI1E8
• Applications: WB
• Recommended Dilution: WB 1:500
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human GMPR (NP_006868) produced in HEK293T cell.
• Formulation: Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
• Reconstitution Method: For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 37.2 kDa
• Gene Name: Homo sapiens guanosine monophosphate reductase (GMPR), mRNA.
• Database Link:
  NP_006868
  Entrez Gene 2766 Human
  UniProt ID P36959
• Background: This gene encodes an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. The protein also functions in the re-utilization of free intracellular bases and purine nucleosides. [provided by RefSeq, Oct 2009]
• Synonyms: GMPR1

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Purine metabolism