IL15RA Mouse Monoclonal Antibody [Clone ID: OTI3D5]

CAT#: CF812229

Carrier-free (BSA/glycerol-free) IL15RA mouse monoclonal antibody,clone OTI3D5


USD 465.00

4 Weeks*

Size
    • 100 ug

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Specifications

Product Data
Clone Name OTI3D5
Applications FC, WB
Recommended Dilution WB 1:500, FLOW 1:25
Reactivities Human
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 31-267 of human IL15RA (NP_001230468) produced in E.coli.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 28.22 kDa
Gene Name Homo sapiens interleukin 15 receptor subunit alpha (IL15RA), transcript variant 3, mRNA.
Background This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq, Apr 2010]
Synonyms CD215
Reference Data
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.