KAT5 Mouse Monoclonal Antibody [Clone ID: OTI6E1]

CAT#: CF812334

Carrier-free (BSA/glycerol-free) KAT5 mouse monoclonal antibody,clone OTI6E1

Product Images

Western blot analysis of extracts (35ug) from cell lines and/or tissue lysates by using anti-KAT5 monoclonal antibody (1:500).

Specifications

Product Data

• Clone Name: OTI6E1
• Applications: WB
• Recommended Dilution: WB 1:500
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 227-504 of human KAT5 (NP_006379) produced in E.coli.
• Formulation: Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
• Reconstitution Method: For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 58.4 kDa
• Gene Name: Homo sapiens lysine acetyltransferase 5 (KAT5), transcript variant 2, mRNA.
• Database Link:
  NP_006379
  Entrez Gene 81601 MouseEntrez Gene 192218 RatEntrez Gene 10524 Human
  UniProt ID Q92993
• Background: The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
• Synonyms: cPLA2; ESA1; HTATIP; HTATIP1; PLIP; TIP; TIP60; ZC2HC5

Reference Data

• Protein Families: Druggable Genome, Transcription Factors