MICB Mouse Monoclonal Antibody [Clone ID: OTI4C8]

CAT#: CF813587

Carrier-free (BSA/glycerol-free) MICB mouse monoclonal antibody, clone OTI4C8

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  View other "OTI4C8" antibodies (2)

USD 465.00

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Size
    • 100 ug

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Specifications

Product Data
Clone Name OTI4C8
Applications FC
Recommended Dilution FLOW 1:100
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 23-309 of human MICB (NP_005922) produced in E.coli.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 42.4 kDa
Gene Name Homo sapiens MHC class I polypeptide-related sequence B (MICB), transcript variant 1, mRNA.
Background This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Synonyms PERB11.2
Reference Data
Protein Families Druggable Genome
Protein Pathways Natural killer cell mediated cytotoxicity

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