Cd8a Rat Monoclonal Antibody [Clone ID: YTS169.4]

CAT#: CL007P

Cd8a rat monoclonal antibody, clone YTS169.4, Purified


USD 475.00

5 Days*

Size
    • 250 ug

Product Images

Specifications

Product Data
Clone Name YTS169.4
Applications FC, IHC
Recommended Dilution Flow cytometry: 1/50-1/100, use 10 µl to label 106 cells in 100 µl. Method sheets are available on request.
Immunohistochemistry on Frozen Sections.
Reactivities Mouse
Host Rat
Isotype IgG2b
Clonality Monoclonal
Specificity This clone recognises the Murine CD8 cell surface antigen, expressed by a subset of T lymphocytes. 
Clone YTS169.4 exhibits depleting activity when used in vivo.
Formulation PBS, pH 7.4
State: Purified
State: Liquid purified IgG fraction from Tissue Culture Supernatant
Preservative: 0.09% Sodium Azide
Concentration 1.0 mg/ml
Purification Affinity Chromatography on Protein G
Background The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
Synonyms CD8 alpha chain, CD8A, MAL
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.