Collagen type III alpha 1 chain Rabbit Polyclonal Antibody

CAT#: CL197P

Collagen type III alpha 1 chain rabbit polyclonal antibody, Aff - Purified

Product Images

Skin: Formalin-Fixed Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: ELISA, IF, IHC
• Recommended Dilution: Indirect Immunofluorescence with Fluorecein anti Rabbit IgG Conjugate, use 1/40 on Frozen bovine skin, and liver tissues.
  Immunohistochemistry on Paraffin Sections: 1/500 on fixed paraffin embedded bovine skin, and liver tissues.
  ELISA: ≥ 1/200 (OD ≥ 500).
  Radioimmunoassay.
  For immunostaining of extra or intracellular components in light microscopy. For the quantitation of Collagen Type III in biological fluids or in culture supernatants.
• Reactivities: Bovine
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Collagen Type III extracted and purified from Bovine skin.
• Specificity: This antibody recognizes Bovine Collagen Type III.
  Specificity (1/50 RIA dilution):
  Bovine Collagen, Type III: 100 %.
  Bovine Collagen, Type I: less than 5.0 %.
  Bovine Collagen, Type II: less than 0.1 %.
• Formulation: State: Aff - Purified
  State: Lyophilized IgG fraction
• Reconstitution Method: Restore with 0.5 ml distilled water.
• Purification: Affinity Chromatography
• Background: Collagen III is a fibrillar collagen that is found in extensible connective tissues such as skin, lung, and the vascular system, frequently in association with type I Collagen. Mutations in the gene are associated with Ehlers Danlos syndrome type IV, and with aortic and arterial aneurysms. Although alternate transcripts have been detected for this gene, they are the result of mutations; these mutations alter splicing, often leading to the exclusion of multiple exons.
• Synonyms: COL3A1