BETVIA Human Monoclonal Antibody [Clone ID: H.G11A9F3.03]

CAT#: DDX0072P-100

BETVIA human monoclonal antibody, clone H.G11A9F3.03


USD 600.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name H.G11A9F3.03
Applications ELISA
Recommended Dilution ELISA (coating), IP. 
Usage recommendation:
*This monoclonal antibody may be used between 5-20 μg/ml.
Reactivities Pollen
Host Human
Isotype IgG4
Clonality Monoclonal
Immunogen human B cells immortalized from a birch pollen allergic patient
Specificity birch pollen Bet v1
Cross-reactivity: large panel of tree’s pollen
Formulation State: Purified
State: 100 μg in 200 μl Tris-NaCl pH 8
Concentration 0.5 mg/ml
Purification QMA Hyper-D Ion-exchange chromatography
Background Birch pollen allergy is a frequent pathology with IgE reactivity against Betv1 the major birch pollen allergen. Human monoclonal antibodies secreting B cells have been cloned from PBMC of allergic patients. These high affinity human monoclonal antibodies raised against BetV1 inhibit the binding of IgE to nitrocellulose-blotted Bet v1 and inhibit histamine release by sensitized basophils. (Visco V. et al, J. Immunol., 1996 ; 157: 956-962 ; Denépoux S et al, FEBS Lett. 2000 Jan 7;465(1):39-46.)
Synonyms BETVI, Allergen Bet v I-A
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.