CD1 (CD1A) Mouse Monoclonal Antibody [Clone ID: 214A9.01]

CAT#: DDX0080A647-100

CD1 (CD1A) mouse monoclonal antibody, clone 214A9.01

Product Images

Facs staining of in vitro-derived DCs with 214A9.01

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  IHC staining of human lung cancer frozen section with clone 214A9 (DDX0080)

Specifications

Product Data

• Clone Name: 214A9.01
• Applications: IF
• Recommended Dilution: Surface flow cytometry.
• Reactivities: Human
• Host: Mouse
• Isotype: IgM
• Clonality: Monoclonal
• Immunogen: in vitro derived human DCs (GMCSF + TNFα)
• Specificity: human CD1a (epitope in extracellular domain).
• Formulation: 100 μg in 200 μl / 50 μg in 100 μl PBS 50% glycerol
  Label: Alexa Fluor 647
• Concentration: lot specific
• Purification: QMA Hyper D ion exchange chromatography
• Conjugation: Alexa Fluor 647
• Storage: -20°C. KEEP CONTENTS STERILE: no preservative.
  Coupled antibodies: glycerol protects from freezing.
• Gene Name: CD1a molecule
• Database Link:
  Entrez Gene 909 Human
  UniProt ID P06126
• Background: CD1 family molecules have a homologous structure to MHC class I. They are monomorphic proteins of 50 kDa non-covalently associated with β2-microglobulin. Human CD1a molecules are divided in 2 groups. Group 1 includes CD1a, CD1b, and CD1c, while group 2 consists of the CD1d molecule. CD1a is mainly expressed at the cell-surface and in recycling vesicles. CD1a occurs in Birbeck’s granules of Langerhans cells and plays a role in presentation of non-peptide antigens. CD1a is expressed in vitro on CD34+ generated DCs and on monocyte-derived DCs. <br /><em>(Burdin N. et al, 1999 ; Curr. Opin. Immunol., 11:326-31 ; Valladeau J. et al, 1999; Immunity, 12:71-81)</em>
• Synonyms: T6/Leu-6, hTa1