CD1 (CD1A) Mouse Monoclonal Antibody [Clone ID: 214A9.01]
Specifications
Product Data | |
Clone Name | 214A9.01 |
Applications | FC, IHC |
Recommended Dilution | IHC, Flow cytometry. |
Reactivities | Human |
Host | Mouse |
Isotype | IgM |
Clonality | Monoclonal |
Immunogen | in vitro derived human DCs (GMCSF + TNFα) |
Specificity | human CD1a (epitope in extracellular domain). |
Formulation | 100 μg in 200 μl / 50 μg in 100 μl PBS 50% glycerol Label: Biotin |
Concentration | lot specific |
Conjugation | Biotin |
Storage | -20°C. KEEP CONTENTS STERILE: no preservative. Coupled antibodies: glycerol protects from freezing. |
Gene Name | CD1a molecule |
Database Link | |
Background | CD1 family molecules have a homologous structure to MHC class I. They are monomorphic proteins of 50 kDa non-covalently associated with β2-microglobulin. Human CD1a molecules are divided in 2 groups. Group 1 includes CD1a, CD1b, and CD1c, while group 2 consists of the CD1d molecule. CD1a is mainly expressed at the cell-surface and in recycling vesicles. CD1a occurs in Birbeck’s granules of Langerhans cells and plays a role in presentation of non-peptide antigens. CD1a is expressed in vitro on CD34+ generated DCs and on monocyte-derived DCs. <br /><em>(Burdin N. et al, 1999 ; Curr. Opin. Immunol., 11:326-31 ; Valladeau J. et al, 1999; Immunity, 12:71-81)</em> |
Synonyms | T6/Leu-6, hTa1 |
Reference Data |
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