CD1 (CD1A) Mouse Monoclonal Antibody [Clone ID: 214A9.01]

CAT#: DDX0080P-100

CD1 (CD1A) mouse monoclonal antibody, clone 214A9.01


USD 440.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name 214A9.01
Applications FC, IHC, WB
Recommended Dilution Flow Cytometry, IHC cryosection, WB.
Reactivities Human
Host Mouse
Isotype IgM
Clonality Monoclonal
Immunogen in vitro derived human DCs (GMCSF + TNFα)
Specificity human CD1a (epitope in extracellular domain).
Formulation 100 μg in 200 μl / 50 μg in 100 μl Tris-NaCl pH 8
State: Purified
Concentration lot specific
Purification QMA Hyper D ion exchange chromatography
Conjugation Unconjugated
Storage -20°C. KEEP CONTENTS STERILE: no preservative.
Purified antibodies: avoid repeated freeze/thaw cycles.
Gene Name CD1a molecule
Background CD1 family molecules have a homologous structure to MHC class I. They are monomorphic proteins of 50 kDa non-covalently associated with β2-microglobulin. Human CD1a molecules are divided in 2 groups. Group 1 includes CD1a, CD1b, and CD1c, while group 2 consists of the CD1d molecule. CD1a is mainly expressed at the cell-surface and in recycling vesicles. CD1a occurs in Birbeck’s granules of Langerhans cells and plays a role in presentation of non-peptide antigens. CD1a is expressed in vitro on CD34+ generated DCs and on monocyte-derived DCs. <br /><em>(Burdin N. et al, 1999 ; Curr. Opin. Immunol., 11:326-31 ; Valladeau J. et al, 1999; Immunity, 12:71-81)</em>
Synonyms T6/Leu-6, hTa1
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.