CD1 (CD1A) Mouse Monoclonal Antibody [Clone ID: 201B5.08]

CAT#: DDX0081A546-100

CD1 (CD1A) mouse monoclonal antibody, clone 201B5.08


USD 530.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name 201B5.08
Applications FC
Recommended Dilution DDX0081A488-50 / DDX0081A488-100 Alexa-fluor®488: Surface flow cytometry, IF.
DDX0081A546-50 / DDX0081A546-100 Alexa- fluor®546 (on request): 
surface Flow Cytometry.
DDX0081A647-50 /DDX0081A647-100 Alexa- fluor®647: 
Surface flow cytometry.
Reactivities Human, Porcine
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen in vitro derived human DCs (GMCSF + TNFα)
Specificity Human CD1a (epitope in extracellular domain).
Species cross- reactivity: Pig.
Formulation Label: Alexa Fluor 546
Concentration lot specific
Purification QMA hyper D ion exchange chromatography
Conjugation Alexa Fluor 546
Storage -20°C. KEEP CONTENTS STERILE: no preservative.
Purified antibodies: avoid repeated freeze/thaw cycles.
Coupled antibodies: glycerol protects from freezing
Gene Name CD1a molecule
Background CD1 family molecules have structural homologies with MHC class I molecules. They are monomorphic proteins of 50 kDa, non-covalently associated with Beta-2-microglobulin. Human CD1a molecules are divided in 2 groups. Group 1 includes CD1a, CD1b, and CD1c, while group 2 consists of the CD1d molecule. CD1a is mainly expressed at the cell-surface and in recycling vesicles. CD1a occurs in Birbeck granules of Langerhans cells and plays a role in presentation of non-peptide antigens. CD1a is expressed in vitro on CD34+-generated DCs and on monocyte-derived DCs. (Burdin N. et al., 1999, Curr Opin Immunol, 11:326-31).
Synonyms T6/Leu-6, hTa1
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.