CD1 (CD1A) Mouse Monoclonal Antibody [Clone ID: 201B5.08]
Specifications
Product Data | |
Clone Name | 201B5.08 |
Applications | FC, IHC |
Recommended Dilution | Surface Flow Cytometry, IHC |
Reactivities | Human, Porcine |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | in vitro derived human DCs (GMCSF + TNFα) |
Specificity | human CD1a (epitope in extracellular domain). Species cross- reactivity: pig. |
Formulation | Label: Biotin |
Concentration | lot specific |
Purification | QMA hyper D ion exchange chromatography |
Conjugation | Biotin |
Storage | -20°C. KEEP CONTENTS STERILE: no preservative. Purified antibodies: avoid repeated freeze/thaw cycles. Coupled antibodies: glycerol protects from freezing |
Gene Name | CD1a molecule |
Database Link | |
Background | CD1 family molecules have structural homologies with MHC class I molecules. They are monomorphic proteins of 50 kDa, non-covalently associated with Beta-2-microglobulin. Human CD1a molecules are divided in 2 groups. Group 1 includes CD1a, CD1b, and CD1c, while group 2 consists of the CD1d molecule. CD1a is mainly expressed at the cell-surface and in recycling vesicles. CD1a occurs in Birbeck granules of Langerhans cells and plays a role in presentation of non-peptide antigens. CD1a is expressed in vitro on CD34+-generated DCs and on monocyte-derived DCs. (Burdin N. et al., 1999, Curr Opin Immunol, 11:326-31). |
Synonyms | T6/Leu-6, hTa1 |
Reference Data |
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