ICAM1 Mouse Monoclonal Antibody [Clone ID: 117G12.02]

CAT#: DDX0150P-100

ICAM1 mouse monoclonal antibody, clone 117G12.02

Product Images

IHC staining of human tonsil paraffin section with clone 117G12 (DX0150)

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  HC staining of human tonsil cyrpt paraffin section with clone 117G12 (DX0150)

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  IHC staining of human lung frozen section with clone 117G12 (DX0150)

Specifications

Product Data

• Clone Name: 117G12.02
• Applications: IHC
• Recommended Dilution: ImmunoHistoChemistry frozen sections, ImmunoHistoChemistry paraffin sections.
  Usage recommendation: *This monoclonal antibody may be used between 1-10 μg/ml.
  
• Reactivities: Human, Sheep
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: in vitro-derived DCs (GM-CSF+TNF)
• Specificity: mAb 117G2 positively stains sheep tissue sections (Schwartz-Cornil I, pers.communication ; Carlson M.et al, 1988, Nucleic Acids Res. 16 (9): 4188; Yang L. et al, 2005, Blood 106 (2): 584).
• Formulation: 100 μg in 200 μl / 50 μg in 100 μl Tris-NaCl pH 8
  State: Purified
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: -20°C. KEEP CONTENTS STERILE: no preservative.
  Purified antibodies: avoid repeated freeze/thaw cycles.
  Coupled antibodies: glycerol protects from freezing.
• Gene Name: intercellular adhesion molecule 1
• Database Link:
  Entrez Gene 3383 Human
  UniProt ID P05362
• Background: 117G12 monoclonal antibody was obtained following mouse immunization with in vitro-derived human dendritic cells. The target antigen was found to be CD54/ICAM-1, a cell surface glycoprotein which is typically expressed on endothelial cells and immune cells. CD54/ICAM-1, member of the Ig superfamily, binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also a receptor for rhinovirus. CD54/ICAM-1 is a type of intracellular adhesion molecule, playing a role in transmigration of endothelial cells into tissues through binding to LFA-1.
• Synonyms: ICAM-1