ICAM1 Mouse Monoclonal Antibody [Clone ID: 217E2.10]

CAT#: DDX0151A546-100

ICAM1 mouse monoclonal antibody, clone 217E2.10


USD 530.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name 217E2.10
Applications FC, IF
Recommended Dilution DDX0151P-50 / DDX0151P-100 Purified: Flow cytometry, IHC (cryosection, paraffin), IF.
DDX0151A488-50 / DDX0151A488-100 Alexa-fluor® 488: Flow cytometry, IF ( On request).
DDX0151A546-50 / DDX0151A546-100 Alexa- fluor® 546: Flow cytometry, IF ( On request).
DDX0151A647-50 / DDX0151A647-100 Alexa- fluor® 647: Flow cytometry, IF ( On request).
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen in vitro-derived DCs (GM-CSF+TNF )
Formulation
Purified:
100 μg in 200 μl / 50 μg in 100 μl Tris-NaCl pH 8.
Coupled: 100 μg in 200 μl / 50 μg in 100 μl PBS 50% glycerol
Label: Alexa Fluor 546
Concentration lot specific
Conjugation Alexa Fluor 546
Storage -20°C. KEEP CONTENTS STERILE: no preservative.
Purified antibodies: avoid repeated freeze/thaw cycles. 
Coupled antibodies: glycerol protects from freezing.
Gene Name intercellular adhesion molecule 1
Background 217E2 monoclonal antibody was obtained following mouse immunization with in vitro-derived human dendritic cells. The target antigen was found to be CD54/ICAM-1, a cell surface glycoprotein which is typically expressed on endothelial cells and immune cells. CD54/ICAM-1, member of the Ig superfamily, binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also a receptor for rhinovirus. CD54/ICAM-1 is a type of intracellular adhesion molecule, playing a role in transmigration of endothelial cells into tissues through binding to LFA-1.
(Carlson M.et al, 1988, Nucleic Acids Res. 16 (9): 4188; Yang L. et al, 2005, Blood 106 (2): 584).
Synonyms ICAM-1
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.