LAMP3 Mouse Monoclonal Antibody [Clone ID: 104G4]

CAT#: DDX0190A488-100

LAMP3 mouse monoclonal antibody, clone 104G4


USD 360.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name 104G4
Applications FC, IF
Recommended Dilution Intracyto Flow cytometry, IF
Reactivities Human, Sheep
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen human DC-LAMP alkaline phosphatase fusion protein
Specificity human DC-LAMP (epitope in intracytoplasmic domain).
Species cross-reactivity: Sheep
Formulation PBS 50% glycerol
Label: Alexa Fluor 488
Concentration lot specific
Conjugation Alexa Fluor 488
Storage -20°C. KEEP CONTENTS STERILE: no preservative.
Coupled antibodies: glycerol protects from freezing.
Gene Name lysosomal associated membrane protein 3
Background The dendritic cell lysosomal-associated membrane protein (DC-LAMP)/CD208 is a type I integral transmembrane glycoprotein mostly homologous to CD68, of about 45 kDa in mouse and 90 kDa in human (glycosylation), with a bipartite C-terminal structure divided by a serine/proline rich region, a transmembrane domain and a conserved tyrosine-based lysosomal targeting motif in its cytoplasmic tail. Initially cloned as a specific marker of human mature dendritic cells (DCs), DC-LAMP has been subsequently shown to be expressed in alveolar type II pneumocytes. In both cell types, the molecule is found in the limiting membrane of intracellular multi-lamellar bodies, known as MIIC (MHC class II compartments) in human mature DCs and as lung surfactant-containing lamellar bodies in type II pneumocytes. In the latter cell type, DC-LAMP expression is also detected at the cell surface.
(de Saint-Vis B et al, 1998 ; Immunity ; 9:325-336)
Synonyms DCLAMP, DC-LAMP, TSC403, Dendritic Cell Marker
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.