Langerin Associated Lectin Mouse Monoclonal Antibody [Clone ID: 109B8.01]
CAT#: DDX0350A546-100
Langerin Associated Lectin mouse monoclonal antibody, clone 109B8.01
Specifications
Product Data | |
Clone Name | 109B8.01 |
Applications | FC, IF |
Recommended Dilution | DDX0350P-50 / DDX0350P-100 Purified: FACS surface, ImmunoHistoChemistry frozen sections, Immunoprecipitation, Western Blot. DDX0350A488-50 / DDX0350A488-100 Alexa-fluor®488: FACS surface, ImmunoFluorescence. DDX0350A546-50 / DDX0350A546-100 Alexa-fluor®546: FACS surface, ImmunoFluorescence. DDX0350A647-50 / DDX0350A647-100 Alexa-fluor®647: FACS surface, ImmunoFluorescence. Usage recommendation: *This monoclonal antibody may be used between 1-10 μg/ml. *Optimal dilution should be determined by each laboratory for each application. *Coupled antibody: to maintain RT before use. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | recombinant human LAL (entire molecule) |
Specificity | Human Langerin associated lectin (LAL). |
Formulation | Purified: 100 μg in 200 μl / 50 μg in 100 μl Tris-NaCl pH 8. Coupled: 100 μg in 200 μl / 50 μg in 100 μl PBS 50% glycerol. Label: Alexa Fluor 546 |
Concentration | 0.5 mg/ml |
Conjugation | Alexa Fluor 546 |
Background | A newly-identified human endothelial cell homolog of the mouse Kupffer-cell receptor (Clec4F, member of C-type lectins) has been cloned from DNA sequence of human langerin. Antibodies against this newly-identified human receptor have been generated and named LAL for Langerinassociated Lectin. These antibodies stain skin, lung and tonsil endothelial cells (unpublished observations). |
Reference Data |
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