Langerin (CD207) Mouse Monoclonal Antibody [Clone ID: 310F7.02/HD26]

CAT#: DDX0361P-100

Langerin (CD207) mouse monoclonal antibody, clone 310F7.02/HD26


USD 440.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name 310F7.02/HD26
Applications ELISA, FC, IHC
Recommended Dilution Paraffin (Bouin) in human section, IHC,ELISA
Reactivities Human, Mouse, Porcine, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen mouse Langerin-transfected eukaryotic cells
Specificity Mouse Langerin (intracellular epitope).
Formulation Tris-NaCl pH 8
State: Purified
Concentration lot specific
Purification QMA Hyper D ion exchange chromatography
Conjugation Unconjugated
Storage -20°C. KEEP CONTENTS STERILE: no preservative.
Purified antibodies: avoid repeated freeze/thaw cycles.
Coupled antibodies: glycerol protects from freezing.
Gene Name CD207 molecule
Background Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. (Valladeau J et al, 2002 J. Immunol, 168 : 782-792) (Douillard P et al, 2005 J Invest Dermatol, 125: 983–994)
Synonyms CLEC4K, Dendritic Cell Marker
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.