Langerin (CD207) Rat Monoclonal Antibody [Clone ID: 929F3.01]

CAT#: DDX0362A546-100

Langerin (CD207) rat monoclonal antibody, clone 929F3.01


USD 530.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name 929F3.01
Applications FC, IF, IHC
Recommended Dilution IF, IHC, Flow cytometry. 
Usage recommendation:

*This monoclonal antibody may be used between 5-20 μg/ml.
*Optimal dilution should be determined by each laboratory for each application.
Reactivities Human, Mouse, Porcine, Rat
Host Rat
Isotype IgG2a
Clonality Monoclonal
Immunogen human Langerin-transfected eukaryotic cells
Specificity Human Langerin.
Species cross-reactivity: Rat, Mouse, Swine.
Formulation 100 μg in 200μl / 50 μg in 100 μl PBS 50% glycerol
Label: Alexa Fluor 546
Concentration lot specific
Conjugation Alexa Fluor 546
Storage Purified antibodies: avoid repeated freeze/thaw cycles.
Coupled antibodies: glycerol protects from freezing.
Gene Name CD207 molecule
Background Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck’s granule. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin expression has not been reported outside the DC system. Human Langerin is involved in the processing of mycobacterial glycolipids leading to antigen presentation to CD1a-restricted T cells. Human Langerin binds the gp120 of HIV. (Valladeau J et al, 2002 J. Immunol, 168 : 782-792; Douillard P et al, 2005 J Invest Dermatol, 125: 983–994; Chorro L. et al, J Exp.Med., 2010, 206 (13), 3089-3100).
Synonyms CLEC4K, Dendritic Cell Marker
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.