Langerin (CD207) Mouse Monoclonal Antibody [Clone ID: 306G9.01/HD24]

CAT#: DDX0368P-100

Langerin (CD207) mouse monoclonal antibody, clone 306G9.01/HD24


USD 440.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name 306G9.01/HD24
Applications FC, IHC
Recommended Dilution Flow cytometry, IF, IHC.

Usage recommendation:
*This monoclonal antibody may be used between 5-20 μg/ml
*Optimal dilution should be determined by each laboratory for each application.
*Coupled antibody: to maintain RT before using.
Reactivities Human, Mouse, Porcine, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Mouse langerin–transfected COP5 cells.
Specificity Mouse and Human Langerin (intracellular epitope).
Species cross- reactivity: Human, Rat, Swine.
Formulation Purified: 100 μg in 200μl / 50 μg in 100 μl Tris-NaCl pH 8.
Coupled: 100 μg in 200μl / 50 μg in 100 μl PBS 50% glycerol.
State: Purified
Concentration lot specific
Purification QMA Hyper D ion exchange chromatography
Conjugation Unconjugated
Storage -20°C. KEEP CONTENTS STERILE: no preservative.
Purified antibodies: avoid repeated freeze/thaw cycles.
Coupled antibodies: glycerol protects from freezing.
Gene Name CD207 molecule
Background Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. In mouse, clone 306G9 stains lymph node dendritic cells (Henri et al, 2001, J. Immunol, 167: 741-748) (Valladeau J. et al, 2002 J Immunol, 168: 782).
Synonyms CLEC4K, Dendritic Cell Marker
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.