Cd207 Mouse Monoclonal Antibody [Clone ID: 205C1]

CAT#: DDX0370A647-100

Cd207 mouse monoclonal antibody, clone 205C1


USD 530.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name 205C1
Applications FC, IF
Recommended Dilution FACS, IF (Douillard P et al, 2005 J. Invest. Dermatol, 125: 983–994). 

Usage recommendation:
*This monoclonal antibody may be used between 5-20 μg/ml.
*Optimal dilution should be determined by each laboratory for each application.
*Coupled antibody: to maintain RT before using.
Reactivities Mouse
Host Mouse
Isotype IgM
Clonality Monoclonal
Immunogen Mouse ear crawl-out Langerhans cells.
Specificity Mouse Langerin.
Formulation Purified: 100 μg in 200μl / 50 μg in 100 μl Tris-NaCl pH 8.
Coupled: 100 μg in 200μl / 50 μg in 100 μl PBS 50% glycerol.
Label: Alexa Fluor 647
Concentration lot specific
Purification Hyper-D ion exchange chromatography
Conjugation Alexa Fluor 647
Storage -20°C. KEEP CONTENTS STERILE: no preservative.
Purified antibodies: avoid repeated freeze/thaw cycles.
Coupled antibodies: glycerol protects from freezing.
Gene Name CD207 antigen
Background Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck’s granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. (Valladeau J et al, 2002 J Immunol, 168 : 782-792) (Douillard P et al, 2005 J Invest Dermatol, 125: 983–994).
Synonyms CLEC4K, Dendritic Cell Marker
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.