Dystonin (DST) Human Monoclonal Antibody [Clone ID: H10D-Hy-8B]

CAT#: DDX0451P-100

Dystonin (DST) human monoclonal antibody, clone H10D-Hy-8B

Specifications

Product Data

• Clone Name: H10D-Hy-8B
• Applications: IF, IHC, WB
• Recommended Dilution: WB, IF, IHC frozen section.
  
  Usage recommendation:
  *This monoclonal antibody may be used between 5-20 μg/ml.
  *Optimal dilution should be determined by each laboratory for each application.
  *Coupled antibody: to maintain RT before using.
  
• Reactivities: Human
• Host: Human
• Isotype: IgG4
• Clonality: Monoclonal
• Immunogen: EBV cell clones derived from PBMC of patients with the typical clinical, histologic, immunopathologic criteria of Bullous Pemphigoid
• Formulation: Purified: 100 μg in 200μl / 50 μg in 100 μl Tris-NaCl pH 8.
  Coupled: 100 μg in 200 μl / 50 μg in 100 μl PBS 50% glycerol.
  State: Purified
• Concentration: lot specific
• Purification: QMA Hyper D ion exchangechromatography
• Conjugation: Unconjugated
• Storage: -20°C. KEEP CONTENTS STERILE: no preservative.
  Purified antibodies: avoid repeated freeze/thaw cycles.
  Coupled antibodies: glycerol protects from freezing.
• Gene Name: dystonin
• Database Link:
  Entrez Gene 667 Human
  UniProt ID Q03001
• Background: Bullous pemphigoid is an acquired blistering skin disease associated with production of IgG autoantibodies to the BP antigen. Antibodies-producing cells were established by EBV infection of CD40-activated PBMCs. These antibodies recognize different epitopes of BPAg1. (Peyron E. et al.,.J Immunol,1994,153, 1333)
• Synonyms: Hemidesmosomal plaque protein, Dystonia musculorum protein, BPA, Bullous pemphigoid antigen, DST, BPAG1, DMH, DT, KIAA0728