TSLP Mouse Monoclonal Antibody [Clone ID: 214E4.01]
Specifications
Product Data | |
Clone Name | 214E4.01 |
Applications | IHC |
Recommended Dilution | DDX0800P-50 / DDX0800P-100 Purified: Immunohistochemistry on Frozen sections. Usage recommendation: *This monoclonal antibody may be used between 1-10 μg/ml. *Optimal dilution should be determined by each laboratory for each application. *Coupled antibody: to maintain RT before use. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | human TSLP-His transfected 293T. |
Specificity | human TSLP. |
Formulation | Purified: 100 μg in 200μl / 50 μg in 100 μl Tris-NaCl pH 8. Coupled: 100 μg in 200μl / 50 μg in 100 μl Tris PBS 50% glycerol. State: Purified |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage | -20°C. KEEP CONTENTS STERILE: no preservative. Purified antibodies: avoid repeated freeze/thaw cycles. Coupled antibodies: glycerol protects from freezing. |
Gene Name | thymic stromal lymphopoietin |
Database Link | |
Background | The TSLP (thymic stromal lymphopoïetin) is a hemopoietic protein of 159 aa (18 kDa), proposed to signal through a heterodimeric receptor complex composed of TSLP-receptor and IL7R chain. Expressed in many tissues, it prevents apoptosis and stimulates the growth of myeloid cells. It is also detected in the thymus and the tissue cells of the bone marrow. TSLP affects the transition from pre-B cells in B. Alternative splicing of this gene results in two transcripts variants. (Reche PA et al, J Immunol., 2001, 167(1):336-43 ; Dorshkind. K, Nature. Immunol., 2000 (1):369-370). |
Synonyms | Thymic stromal lymphopoietin, Thymic stroma-derived lymphopoietin |
Reference Data |
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