Mabthera (Rituximab) Mouse Monoclonal Antibody [Clone ID: 109H9.06]

CAT#: DDX5010B-100

Mabthera (Rituximab) mouse monoclonal antibody, clone 109H9.06

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Specifications

Product Data

• Clone Name: 109H9.06
• Applications: ELISA
• Recommended Dilution: DDX5010P-50 / DDX5010P-100 Purified: Bridging Elisa positive control for anti-Mabthera detection,
  Capture antibody for anti-Mabthera detection.
  DDX5010B-50 DDX5010B-100 Biotin: Detection antibody for Mabthera detection.
  
  DDX5011P-50 / DDX5011P-100 Purified: Bridging Elisa positive control for anti-Mabthera detection.
  DDX5011B-50 DDX5011B-100 Biotin: Detection antibody for Mabthera detection.
  
  Usage recommendation:
  *This monoclonal antibody may be used between 5-25μg/ml.
  *Optimal dilution should be determined by each laboratory for each application.
  *Coupled antibody: to maintain RT before use.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Mabthera® (Roche) (Rituximab)
• Specificity: Mabthera ® (Rituximab), negative for remicade (infliximab) and roactemra (tocilizumab).
  Cross-reactivity: Negative for remicade (infliximab) and roactemra (tocilizumab).
• Formulation: Purified: 100 μg in 200 μl / 50 μg in 100 μl Tris-NaCl pH 8.
  Coupled: 100 μg in 200 μl / 50 μg in 100 μl PBS 50% glycerol.
  Label: Biotin
• Concentration: 0.5 mg/ml
• Purification: QMA Hyper D ion exchange chromatography
• Conjugation: Biotin
• Background: Mabthera ® (Rituximab) is a chimeric monoclonal antibody targeting the CD20 protein expressed on B cell surface. Mabthera ® (Rituximab ) destroys B cells and is therefore used to treat diseases such as lymphomas, leukemias, transplant rejection, and autoimmune disorders. Mabthera® (Rituximab) has also been shown to be an effect ive rheumatoid arthritis treatment, in cases where anti - TNF - alpha therapy is not satisfactory. We have generated a panel of anti - Mabthera® (anti - Rituximab) monoclonal murine antibodies. These antibodies can be used to develop and calibrate Mabthera (Rituximab) and anti - Mabthera (anti - Rituximab) detection assays.