IL1 beta (IL1B) Mouse Monoclonal Antibody [Clone ID: S3F12]

CAT#: DM1024

IL1 beta (IL1B) mouse monoclonal antibody, clone S3F12, Purified

Specifications

Product Data

• Clone Name: S3F12
• Applications: ELISA
• Recommended Dilution: ELISA.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant human IL1 beta
• Specificity: Reactive with natural and recombinant Human Interleukin-1 beta (IL1 beta).
  Does not show any cross reaction with recombinant Human IL1 alpha, recombinant Murine IL1 alpha or IL1 beta.
• Formulation: 0.01M PBS, pH 7.2 without preservatives.
  State: Purified
  State: Lyophilized purified IgG fraction.
• Reconstitution Method: Restore with double distillated water to adjust the final concentration to 1.00 mg/ml
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein G.
• Conjugation: Unconjugated
• Storage: Store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens interleukin 1, beta (IL1B)
• Database Link:
  Entrez Gene 3553 Human
  UniProt ID P01584
• Background: Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types, and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin1 alpha (IL1 alpha) and interleukin1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25% homology in their amino acid sequence.
• Synonyms: IL-1 beta, IL1B, IL1 beta, IL1F2, Catabolin

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Alzheimer's disease, Apoptosis, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Graft-versus-host disease, Hematopoietic cell lineage, MAPK signaling pathway, NOD-like receptor signaling pathway, Prion diseases, Toll-like receptor signaling pathway, Type I diabetes mellitus