IL16 Mouse Monoclonal Antibody [Clone ID: 59]

CAT#: DM1025

IL16 mouse monoclonal antibody, clone 59, Purified

Specifications

Product Data

• Clone Name: 59
• Applications: ELISA, WB
• Recommended Dilution: ELISA.
  Western Blot: IL16 antibody at a concentration of 2.5 µg/ml will allow visualization of 1 ug/lane of human IL-16.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Purified recombinant Human IL-16.
• Specificity: This antibody reacts to Interleukin-16.
  IL16 antibody clone 323 exhibits no detectable cross-reacting with human albumin serum, Bovine albumin serum and other human cytokines or growth factors tested such as IL-1beta, IL-8, IL-7 MCAF, TGF-beta 1, EGF, bFGF, GM-CSF, M-CSF, TNF-alpha.
• Formulation: 0.01M PBS, pH 7.2 without preservatives.
  State: Purified
  State: Lyophilized purified IgG fraction.
• Reconstitution Method: Restore with double distillated water to adjust the final concentration to 1.00 mg/ml.
• Purification: Affinity Chromatography on Protein G.
• Conjugation: Unconjugated
• Storage: Store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens interleukin 16 (IL16), transcript variant 1
• Database Link:
  Entrez Gene 3603 Human
  UniProt ID Q14005
• Background: Interleukin-16 (IL16) is a proinflammatory cytokine that is chemotactic for CD4+ T lymphocytes, monocytes, and eosinophils. IL16 is synthesized as a precursor molecule (pro IL16) of approximately 68 kDa and 631 amino acid residues lacking a signal peptide. The sequence and structure of IL16 is conserved across species. In addition to inducing chemotaxis, IL16 upregulates the IL2 receptor and upregulates HLADR expression. It also inhibits T cell receptor (TCR)/CD3 dependent activation, and suppresses HIV1 replication in vitro. Sources of IL16 include epithelial cells, mast cells, T lymphocytes (CD4+ and CD8+), macrophages, synovial fibroblasts, and eosinophils.
• Synonyms: IL-16, LCF

Reference Data

• Protein Families: Druggable Genome, Secreted Protein