IL16 Mouse Monoclonal Antibody [Clone ID: 323]

CAT#: DM1027HRP

IL16 mouse monoclonal antibody, clone 323, HRP

Specifications

Product Data

• Clone Name: 323
• Applications: ELISA
• Recommended Dilution: ELISA: In combination with capture antibody Clone 398 (Cat.-No DM1026), this HRP conjugated antibody can be used as a tracer antibody for Human IL-16 detection.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Purified recombinant Human IL-16
• Specificity: This antibody reacts with natural and recombinant IL-16.
  No cross-reactivity with Human Serum Albumin, Bovine Serum Albumin and other cytokines or growth factors tested such as IL-1beta, TGF-beta1, TNF-alpha, IL-8, IL-7, MCP-1, EGF, bFGF, GM-CSF.
• Formulation: 0.01M PBS, pH 7.0 ± 0.1 in 50% Glycerol and 0.01% Thimerosal as a bacteriostat
  Label: HRP
  State: Liquid purified IgG fraction
  Label: Horseradish Peroxidase
• Purification: Affinity Chromatography on Protein G
• Conjugation: HRP
• Storage: Upon receipt, store (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens interleukin 16 (IL16), transcript variant 1
• Database Link:
  Entrez Gene 3603 Human
  UniProt ID Q14005
• Background: IL16 is a proinflammatory cytokine that is chemotactic for CD4+ T lymphocytes, monocytes, and eosinophils. IL16 is synthesized as a precursor molecule (pro IL16) of approximately 68 kDa and 631 amino acid residues lacking a signal peptide. The sequence and structure of IL16 is conserved across species. In addition to inducing chemotaxis, IL16 upregulates the IL2 receptor and upregulates HLADR expression. It also inhibits T cell receptor (TCR)/CD3 dependent activation, and suppresses HIV1 replication in vitro. Sources of IL16 include epithelial cells, mast cells, T lymphocytes (CD4+ and CD8+), macrophages, synovial fibroblasts, and eosinophils.
• Synonyms: IL-16, LCF

Reference Data

• Protein Families: Druggable Genome, Secreted Protein