CEACAM20 Mouse Monoclonal Antibody [Clone ID: HT-12D8]

CAT#: DM1231

CEACAM20 mouse monoclonal antibody, clone HT-12D8, Purified


USD 380.00

2 Weeks*

Size
    • 100 ug

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Specifications

Product Data
Clone Name HT-12D8
Applications ELISA, FC, IF, WB
Recommended Dilution Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400.
ELISA (capture): With clone HD-6G4-A5 as detection antibody.
Flow cytometry: 1.2 µg/10e6 cells.
Immunofluorescence: 1 µg/10e6 cells.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Genetic immunisation with cDNA encoding Human CEACAM20.
Specificity Recognizes CEACAM20
Formulation Phosphate buffered saline, pH 7.2
State: Purified
State: Liquid purified Ig fraction.
Concentration 2.0 mg/ml
Purification Affinity Chromatography on Protein G.
Gene Name Homo sapiens carcinoembryonic antigen related cell adhesion molecule 20 (CEACAM20), transcript variant 5L
Background CEA-related cell adhesion molecule 20 (CEACAM20) belongs to the carcinoembryonic antigen (CEA) gene family (1). It encodes a putative glycoprotein which is membrane-bound via a transmembrane domain. The CEACAM20 protein contains a single N domain followed by 4 immunoglobulin-like A (A1, A2) and B (B1, B2) domains. Expression of CEACAM20 can be found in tissues of prostate, testis, duodenum and small intestine with highest expression in prostate. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria. High expression of CEACAM20 in tissue of prostate carcinoma and in prostate carcinoma cell lines suggest that CEACAM20 can be used as a tumor marker.
Synonyms GPAD9366; UNQ9366
Note SDS-PAGE analysis: The antibody was purified by protein G affinity chromatography from cell culture supernatants and verified by SDS-Page (Figure.4).
Reference Data
Protein Families Transmembrane

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.