MCP1 (CCL2) Mouse Monoclonal Antibody [Clone ID: 9G10]

CAT#: DM2031

MCP1 (CCL2) mouse monoclonal antibody, clone 9G10, Azide Free


USD 540.00

2 Weeks*

Size
    • 500 ug

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Specifications

Product Data
Clone Name 9G10
Applications ELISA, FN
Recommended Dilution ELISA: React with Human MCP-1.
Neutralizing: Tests on the ability to inhibit monocyte chemotaxis toward 1 nM recombinant human MCP-1 in blindwell chambers showed that the antibodies were particularly effective on blocking MCP1 activity.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Purified recombinant Human MCP1.
Specificity This MCP1 antibody reacts with natural and recombinant Human MCP-1.
Does not react with Human Interleukin-8 (IL-8) and other human cytokines tested such as interleukin-1 beta (IL1 beta), serum Amyloid A (SAA) and epidermal growth factor (EGF).
Formulation 0.01M PBS, pH 7.2 without preservatives.
State: Azide Free
State: Lyophilized purified IgG fraction.
Reconstitution Method Restore with double distillated water to adjust the final concentration to 1.00 mg/ml
Purification Affinity Chromatography on Protein G.
Conjugation Unconjugated
Storage Store the antibody at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens C-C motif chemokine ligand 2 (CCL2)
Background This chemotactic factor attracts monocytes and basophils but not neutrophils or eosinophils and augments monocyte anti-tumor activity. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. It may be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.
Synonyms C-C motif chemokine 2, SCYA2, MCAF, Small-inducible cytokine A2, MCP-1, HC11, HC-11
Reference Data
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Chemokine signaling pathway, Cytokine-cytokine receptor interaction, NOD-like receptor signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.