MCP1 (CCL2) Mouse Monoclonal Antibody [Clone ID: S101]

CAT#: DM2034B

MCP1 (CCL2) mouse monoclonal antibody, clone S101, Biotin


USD 590.00

2 Weeks*

Size
    • 100 ul

Product Images

Specifications

Product Data
Clone Name S101
Applications ELISA
Recommended Dilution ELISA: This Biotin-conjugated monoclonal antibody can be used as a Tracer/Detection antibody in Sandwich ELISA applications for Human MCP-1 detection in combination with a Capture antibody Clone S14 (Cat.-No DM2032) and avidin-HRP conjugate.
Suggested Capture Coating Dose: ~0.3 µg/ml; Substrate: TMB. If the above suggested conditions are followed approximately 1.5 pg/mL of MCP-1 in serum/plasma or 4 pg/mL of MCP-1 in medium can be detected with an assay range of 0-1600 pg/mL.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Purified recombinant Human MCP-1
Specificity This monoclonal antibody reacts with natural and recombinant Human MCP-1.
Does not react with Human interleukin-8 (IL-8) and other human cytokines tested such as interleukin-1β (IL-1β), serum amyloid A (SAA) and epidermal growth factor (EGF).
Formulation 0.01M PBS, pH 7.0±0.1
Label: Biotin
State: Liquid purified IgG fraction
Stabilizer: 1% Gelatin
Preservative: 0.1% Proclin-300
Purification Affinity Chromatography on Protein G
Conjugation Biotin
Storage Upon receipt, store (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name C-C motif chemokine ligand 2
Background Monocyte chemotactic and activating factor (MCAF) is also called monocyte chemotactic protein-1 (MCP-1) and chemokine (C-C motif) ligand 2 (CCL2). It is primarily secreted by monocytes, macrophages and dendritic cells. This cytokine displays chemotactic activity for monocytes, T-cells, and basophils, but not for neutrophils or eosinophils. MCAF causes the degranulation of basophils and mast cells, and augments the activity of monocyte and macrophage. MCAF plays an important role in inflammation, angiogenesis, auto-immune diseases, renal diseases, chronic infection and granuloma formation.
Synonyms C-C motif chemokine 2, SCYA2, MCAF, Small-inducible cytokine A2, MCP-1, HC11, HC-11
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.