MCP3 (CCL7) Mouse Monoclonal Antibody [Clone ID: 1057]

CAT#: DM2041

MCP3 (CCL7) mouse monoclonal antibody, clone 1057, Purified

Specifications

Product Data

• Clone Name: 1057
• Applications: ELISA, WB
• Recommended Dilution: ELISA.
  Western Blot: CCL7 antibody concentration of 2-6 µg/mL will allow visualization of 0.1 µg/lane of Human MCP-3.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant Human MCP-3 (M.W. 8.5 kDa containing 76 amino acids residues)
• Specificity: Reactive with natural and recombinant human MCP-3.
  Does not show any cross reaction with other Human Cytokines or growth factors tested such as IL1 beta, IL-8, MCAF, SAA and EGF
• Formulation: 0.01M PBS, pH 7.2 without preservatives.
  State: Purified
  State: Lyophilized purified IgG fraction.
• Reconstitution Method: Restore with double distillated water to adjust the final concentration to 1.00 mg/ml
• Purification: Affinity Chromatography on Protein G.
• Conjugation: Unconjugated
• Storage: Store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens chemokine (C-C motif) ligand 7 (CCL7)
• Database Link:
  Entrez Gene 6354 Human
  UniProt ID P80098
• Background: MCP3/CCL7 is a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix.
• Synonyms: Small-inducible cytokine A7, CCL-7, MCP-3, C-C motif chemokine 7, SCYA6, SCYA7, NC28

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction, NOD-like receptor signaling pathway