Collagen IV (COL4A1) Mouse Monoclonal Antibody [Clone ID: COL-94]

CAT#: DM229-05

Collagen IV (COL4A1) mouse monoclonal antibody, clone COL-94, Ascites


USD 370.00

3 Days*

Size
    • 500 ul

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Specifications

Product Data
Clone Name COL-94
Applications IHC
Recommended Dilution Immunohistochemistry on formalin-fixed paraffin embedded sections: diluted of 1:25-1:50 in an ABC method (30 minutes at room temperature)
Recommended Positive Control: Skin
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human collagen type IV.
Specificity This antibody recognizes collagen type IV epitope located on the alpha1 and/or alpha 2 chains of human collagen type IV.
This antibody shows no cross reactivity with collagen types I, II, III, V, VI and VII as well as does not react with human vitronectin, fibronectin or chondroitin sulfate A, B and C.
Cellular Localization: Basement membrane
Formulation State: Ascites
State: Ascites containing Sodium Azide as preservative.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens collagen type IV alpha 1 (COL4A1), transcript variant 1
Background Collagen IV is a major constituent of the basement membranes along with laminins, proteoglycans and enactins. It is a multimeric protein composed of 3 alpha subunits. These subunits are encoded by 6 different genes, alpha 1 through alpha 6, each of which can form a triple helix structure with 2 other subunits to form type IV collagen. It can form insoluble fibers with high tensile strength. Collagen IV is useful in detecting the loss of parts of basement membranes in carcinomas.
Synonyms COL4A1
Reference Data
Protein Pathways ECM-receptor interaction, Focal adhesion, Pathways in cancer, Small cell lung cancer

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.