TIE2 (TEK) Mouse Monoclonal Antibody [Clone ID: Cl.16]

CAT#: DM3511RT

TIE2 (TEK) mouse monoclonal antibody, clone Cl.16, PE

Product Images

FACS analysis with primary human dermal lymphatic endothelial cells (HDLEC).

Specifications

Product Data

• Clone Name: Cl.16
• Applications: FC
• Recommended Dilution: FACS analysis and cell sorting: ≤ 0.5 µg/ml in 100 µl.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant human soluble CD202b / TIE-2 protein
• Specificity: The unconjugated monoclonal antibody will detect native human TIE-2 /TEK in ELISA experiments and on the surface of different human cell types.
• Formulation: PBS
  Label: PE
  State: Liquid purified IgG fraction from culture supernatant
  Stabilizer: 1% BSA
  Preservative: 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Protein G Chromatography
• Conjugation: PE
• Storage: Store undiluted at 2-8°C.
  DO NOT FREEZE!
  
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 7010 Human
• Background: TIE2 (tyrosine kinase with Ig and EGF homology domains 2) is expressed almost exclusively in endothelial cells in mice, rats and humans. This receptor possesses a unique extracellular domain containing two immunoglobulin like loops separated by three epidermal growth factor like repeats that are connected to three fibronectin type III like repeats. The ligand for the receptor is Angiopoietin 1. Defects in TIE2 are associated with inherited venous malformations; the TIE2 signaling pathway appears to be critical for endothelial cell smooth muscle cell communication in venous morphogenesis.
• Synonyms: TIE2, TIE-2, Angiopoietin-1 receptor, p140 TEK