Edar Rat Monoclonal Antibody [Clone ID: 9A38]

CAT#: DM3541P

Edar rat monoclonal antibody, clone 9A38, Purified

Specifications

Product Data

• Clone Name: 9A38
• Applications: WB
• Recommended Dilution: Western Blot: 1/500 - 1/1000.
• Reactivities: Human, Mouse
• Host: Rat
• Isotype: IgG2
• Clonality: Monoclonal
• Immunogen: Recombinant extracellular domain of EDAR
• Specificity: This antibody detects EDAR and cross reacts with human EDAR.
• Formulation: State: Purified
  State: Lyophilized purified Ig
• Reconstitution Method: Restore with 200µl sterile PBS and the final concentration is 500µg/ml.
• Purification: Protein A/G affinity chromatography
• Database Link:
  Entrez Gene 13608 Mouse
• Background: EDAR (Ectodysplasin A receptor) is a receptor for EDA isoform A1, but not for EDA isoform A2. It has a single transmembrane domain, and shows similarity to 2 separate domains of the tumor necrosis factor (TNF) receptor (TNFR) family. It mediates the activation of NF-kappa-B and JNK and may promote caspase independent cell death. Defects in EDAR are a cause of hypohidrotic ectodermal dysplasia.
• Synonyms: Ectodysplasin-A receptor, EDA-A1 receptor, DL, ED3, ED5, ED1R, EDA3, HRM1, EDA1R, EDA-A1R, FLJ94390