HRG Rat Monoclonal Antibody [Clone ID: 9G42]

CAT#: DM3554P

HRG rat monoclonal antibody, clone 9G42, Purified

Specifications

Product Data

• Clone Name: 9G42
• Applications: WB
• Recommended Dilution: Western Blot: 1/500-1/1000.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2
• Clonality: Monoclonal
• Immunogen: Purified Mouse Recombinant HPRG protein
• Specificity: This antibody detects Mouse HPRG in Western blotting.
• Formulation: PBS
  State: Purified
  State: Lyophilized purified IgG fraction
  Stabilizer: None
• Reconstitution Method: Restore with 0.2 ml sterile PBS and the final concentration is 0.5 mg/ml
• Purification: Affinity Chromatography on Protein A/G. 0.2 µm Filteration.
• Storage: Shelf life: one year from despatch.
  Prior to reconstitution store at 2-8°C.
  Following reconstitution store undiluted at 2-8°C for one month
  or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens histidine rich glycoprotein (HRG)
• Database Link:
  Entrez Gene 3273 Human
• Background: HRG (histidine-rich glycoprotein) contains two cystatin-like domains and is located in plasma and platelets. The physiological function is not yet known. It binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin, and the lysine-binding site of plasminogen. A potential prothrombotic effect of HRG is indicated by the inhibition of fibrinolysis and the reduction of inhibition of coagulation. Mutations in HRG lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.
• Synonyms: Histidine-proline-rich glycoprotein, HPRG

Reference Data

• Protein Families: Secreted Protein