Igfbp2 Rat Monoclonal Antibody [Clone ID: 8J27]

CAT#: DM3559P

Igfbp2 rat monoclonal antibody, clone 8J27, Purified

Specifications

Product Data

• Clone Name: 8J27
• Applications: WB
• Recommended Dilution: Western Blot: 1/500 - 1/1000.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2
• Clonality: Monoclonal
• Immunogen: Recombinant protein of IGF-BP2
• Specificity: This antibody detects IGF-BP2. No cross activity to other IGFBPs.
• Formulation: State: Purified
  State: Lyophilized purified Ig
• Reconstitution Method: Restore with 200µl sterile PBS and the final concentration is 500µg/ml.
• Purification: Protein A/G affinity chromatography
• Database Link:
  Entrez Gene 16008 Mouse
• Background: IGFBP2 (insulin-like growth factor binding protein 2) is a member of the ISGBP family which bind various IGFs. IGFBP2 is overexpressed in a wide spectrum of other cancers, including glioma, prostate cancer, synovial sarcoma, neuroblastoma, colon cancer, adrenocortical cancer, lung cancer, Wilms' tumor, and hepatoblastoma. The overexpression of IGFBP2 also correlates with the aggressiveness of some tumors. IGFBP2 activates the expression of matrix metalloprotease 2, which contributes to cell invasiveness.
• Synonyms: IGF-binding protein 2, IGFBP-2, IBP2, IBP-2